—— About the Lab

Research at the intersection of genetics, epigenomics, and cardiac biology.

The Goldman Lab is located within the Ohio State Biochemistry Program at The Ohio State University. We combine zebrafish genetics, next-generation sequencing, and molecular biology to dissect the mechanisms of heart regeneration.

Dr. Goldman is an investigator at the Ohio State Biochemistry Program, where his laboratory focuses on the molecular mechanisms that govern cardiac regeneration in Danio rerio (zebrafish). His research bridges developmental biology, epigenomics, and cardiovascular medicine.

Using transgenic and mutant zebrafish models, Dr. Goldman's group dissects the specific molecules that regulate transcription and chromatin dynamics in the zebrafish heart after injury — seeking to uncover new paradigms that distinguish heart regeneration in zebrafish from scarring and myopathy in humans.

His long-term goal is to translate insights from zebrafish biology into actionable therapeutic strategies for human cardiac disease — one of medicine's most significant unmet challenges.

—— BIOGRAPHY

Dr. Joseph Aaron Goldman, PhD

How We Work

  • RIGOR

    Reproducibility First
    Every result is verified across multiple experimental replicates and biological conditions. We practice open science and make data freely available upon publication.

  • MENTORSHIP

    Career Development
    Weekly one-on-ones, structured training plans, and a collaborative environment designed to support researchers at every career stage — from undergrad to postdoc.

  • COLLABORATION

    Cross-Disciplinary
    We work closely with cardiologists, computational biologists, and structural biologists both at OSU and at partner institutions around the world.

—— PEOPLE

The Team

  • Dr. Aaron Goldman
    Principal Investigator

    PhD, Molecular Biology. Leads research on zebrafish cardiac regeneration, chromatin dynamics, and translational genomics.

  • Postdoctoral Researcher
    Position Open

    We are actively recruiting a postdoc with expertise in zebrafish biology, epigenomics, or cardiovascular genetics.

  • Graduate Students
    PhD Candidates

    Rotation students from the OSU IBGP and Biochemistry programs are welcome to contact us about potential projects.